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Finger length ratio may predict osteoarthritis
Written by JuniorDr Team   
Thursday, 28 February 2008

People whose index finger is shorter than their ring finger are at higher risk of osteoarthritis (OA), according to a study published in the journal Arthritis and Rheumatism.

fingerpoint_small.jpgThe results suggests that people whose index finger is shorter than their ring finger are up to twice as likely to suffer from the condition, which is the most common form of arthritis.

"The underlying mechanism of the risk is unclear," said Professor Michael Doherty, lead researcher, "and merits further exploration."

Index to ring finger length ratio (referred to as 2D: 4D) is a trait known for its differences between the sexes. Men typically have shorter second than fourth digits; in women, these fingers tend to be about equal in length.

Researchers at The University of Nottingham conducted a case-control study of over 2,000 patients to assess the relationship between the 2D: 4D ratio and the risk of knee and hip OA. Their findings suggest that having a relatively low index finger to ring finger ratio raises the risk for developing OA of the knee, independent of other risk factors and particularly among women.

"The 2D: 4D length ratio appears to be a new risk factor for the development of OA," said Professor Doherty.  "Specifically, women with the 'male' pattern of 2D: 4D length ratio - that is, ring finger relatively longer than the index finger - are more likely to develop knee OA."

Smaller 2D: 4D ratios have intriguing hormonal connections, including higher prenatal testosterone levels, lower oestrogen concentrations, and higher sperm counts. Reduction in this ratio has also been linked to athletic and sexual prowess.

http://www.interscience.wiley.com/journal/arthritis
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